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Volume 6 Supplement 2

Computational Vaccinology: State-of-the-art Assessments

  1. Immunoinformatics is an emergent branch of informatics science that long ago pullulated from the tree of knowledge that is bioinformatics. It is a discipline which applies informatic techniques to problems of ...

    Authors: Darren R Flower, Isabel K Macdonald, Kamna Ramakrishnan, Matthew N Davies and Irini A Doytchinova

    Citation: Immunome Research 2010 6(Suppl 2):S1

    Content type: Review

    Published on:

  2. Identification of epitopes that invoke strong responses from B-cells is one of the key steps in designing effective vaccines against pathogens. Because experimental determination of epitopes is expensive in te...

    Authors: Yasser EL-Manzalawy and Vasant Honavar

    Citation: Immunome Research 2010 6(Suppl 2):S2

    Content type: Review

    Published on:

  3. Atomistic Molecular Dynamics provides powerful and flexible tools for the prediction and analysis of molecular and macromolecular systems. Specifically, it provides a means by which we can measure theoreticall...

    Authors: Darren R Flower, Kanchan Phadwal, Isabel K Macdonald, Peter V Coveney, Matthew N Davies and Shunzhou Wan

    Citation: Immunome Research 2010 6(Suppl 2):S4

    Content type: Review

    Published on:

  4. Viruses are fast evolving pathogens that continuously adapt to the highly variable environments they live and reproduce in. Strategies devoted to inhibit virus replication and to control their spread among hos...

    Authors: Samuel Ojosnegros and Niko Beerenwinkel

    Citation: Immunome Research 2010 6(Suppl 2):S5

    Content type: Review

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  5. To properly characterize protective polyclonal antibody responses, it is necessary to examine epitope specificity. Most antibody epitopes are conformational in nature and, thus, cannot be identified using synt...

    Authors: Galina F Denisova, Dimitri A Denisov and Jonathan L Bramson

    Citation: Immunome Research 2010 6(Suppl 2):S6

    Content type: Review

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  6. The last years have seen a renaissance of the vaccine area, driven by clinical needs in infectious diseases but also chronic diseases such as cancer and autoimmune disorders. Equally important are technologica...

    Authors: Johannes Söllner, Andreas Heinzel, Georg Summer, Raul Fechete, Laszlo Stipkovits, Susan Szathmary and Bernd Mayer

    Citation: Immunome Research 2010 6(Suppl 2):S7

    Content type: Research

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